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Site‐Selective Modification of Peptides and Proteins via Interception of Free‐Radical‐Mediated Dechalcogenation

The development of site‐selective chemistry targeting the canonical amino acids enables the controlled installation of desired functionalities into native peptides and proteins. Such techniques facilitate the development of polypeptide conjugates to advance therapeutics, diagnostics, and fundamental...

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Detalles Bibliográficos
Autores principales: Griffiths, Rhys C., Smith, Frances R., Long, Jed E., Williams, Huw E. L., Layfield, Robert, Mitchell, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756370/
https://www.ncbi.nlm.nih.gov/pubmed/32893423
http://dx.doi.org/10.1002/anie.202006260