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Site‐Selective Modification of Peptides and Proteins via Interception of Free‐Radical‐Mediated Dechalcogenation
The development of site‐selective chemistry targeting the canonical amino acids enables the controlled installation of desired functionalities into native peptides and proteins. Such techniques facilitate the development of polypeptide conjugates to advance therapeutics, diagnostics, and fundamental...
Autores principales: | Griffiths, Rhys C., Smith, Frances R., Long, Jed E., Williams, Huw E. L., Layfield, Robert, Mitchell, Nicholas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756370/ https://www.ncbi.nlm.nih.gov/pubmed/32893423 http://dx.doi.org/10.1002/anie.202006260 |
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