A Stearoyl–Coenzyme A Desaturase Inhibitor Prevents Multiple Parkinson Disease Phenotypes in α‐Synuclein Mice

OBJECTIVE: Parkinson disease (PD) has useful symptomatic treatments that do not slow the neurodegenerative process, and no significant disease‐modifying treatments are approved. A key therapeutic target in PD is α‐synuclein (αS), which is both genetically implicated and accumulates in Lewy bodies ri...

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Detalles Bibliográficos
Autores principales: Nuber, Silke, Nam, Alice Y., Rajsombath, Molly M., Cirka, Haley, Hronowski, Xiaoping, Wang, Junmin, Hodgetts, Kevin, Kalinichenko, Liubov S., Müller, Christian P., Lambrecht, Vera, Winkler, Jürgen, Weihofen, Andreas, Imberdis, Thibaut, Dettmer, Ulf, Fanning, Saranna, Selkoe, Dennis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756464/
https://www.ncbi.nlm.nih.gov/pubmed/32996158
http://dx.doi.org/10.1002/ana.25920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756464/
https://www.ncbi.nlm.nih.gov/pubmed/32996158
http://dx.doi.org/10.1002/ana.25920

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