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The Diversity of a Polyclonal FluCell‐SELEX Library Outperforms Individual Aptamers as Emerging Diagnostic Tools for the Identification of Carbapenem Resistant Pseudomonas aeruginosa

Textbook procedures require the use of individual aptamers enriched in SELEX libraries which are subsequently chemically synthesized after their biochemical characterization. Here we show that this reduction of the available sequence space of large libraries and thus the diversity of binding molecul...

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Detalles Bibliográficos
Autores principales: Kubiczek, Dennis, Raber, Heinz, Bodenberger, Nicholas, Oswald, Thomas, Sahan, Melis, Mayer, Daniel, Wiese, Sebastian, Stenger, Steffen, Weil, Tanja, Rosenau, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756519/
https://www.ncbi.nlm.nih.gov/pubmed/32515842
http://dx.doi.org/10.1002/chem.202000213