Relationship between sodium channel function and clinical phenotype in SCN5A variants associated with Brugada syndrome

The identification of a pathogenic SCN5A variant confers an increased risk of conduction defects and ventricular arrhythmias (VA) in Brugada syndrome (BrS). However, specific aspects of sodium channel function that influence clinical phenotype have not been defined. A systematic literature search id...

Descripción completa

Detalles Bibliográficos
Autores principales: Pearman, Charles M., Denham, Nathan C., Mills, Robert W., Ding, Wern Y., Modi, Simon S., Hall, Mark C. S., Todd, Derick M., Mahida, Saagar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756571/
https://www.ncbi.nlm.nih.gov/pubmed/33131149
http://dx.doi.org/10.1002/humu.24128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756571/
https://www.ncbi.nlm.nih.gov/pubmed/33131149
http://dx.doi.org/10.1002/humu.24128

Ejemplares similares