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Fibulin 5, a human Wharton's jelly‐derived mesenchymal stem cells‐secreted paracrine factor, attenuates peripheral nervous system myelination defects through the Integrin‐RAC1 signaling axis

In the peripheral nervous system (PNS), proper development of Schwann cells (SCs) contributing to axonal myelination is critical for neuronal function. Impairments of SCs or neuronal axons give rise to several myelin‐related disorders, including dysmyelinating and demyelinating diseases. Pathologica...

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Detalles Bibliográficos
Autores principales: Won, So Yeon, Kwon, Soojin, Jeong, Hui Su, Chung, Ki Wha, Choi, Byung‐Ok, Chang, Jong Wook, Lee, Ji Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756588/
https://www.ncbi.nlm.nih.gov/pubmed/33107705
http://dx.doi.org/10.1002/stem.3287