Genotoxicity as a toxicologically relevant endpoint to inform risk assessment: A case study with ethylene oxide

The purpose of the present investigation is to analyze the in vivo genotoxicity dose–response data of ethylene oxide (EO) and the applicability of the derived point‐of‐departure (PoD) values when estimating permitted daily exposure (PDE) values. A total of 40 data sets were identified from the liter...

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Detalles Bibliográficos
Autores principales: Gollapudi, Bala Bhaskar, Su, Steave, Li, Abby A., Johnson, George E., Reiss, Richard, Albertini, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756744/
https://www.ncbi.nlm.nih.gov/pubmed/32926486
http://dx.doi.org/10.1002/em.22408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756744/
https://www.ncbi.nlm.nih.gov/pubmed/32926486
http://dx.doi.org/10.1002/em.22408

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