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Genotoxicity as a toxicologically relevant endpoint to inform risk assessment: A case study with ethylene oxide
The purpose of the present investigation is to analyze the in vivo genotoxicity dose–response data of ethylene oxide (EO) and the applicability of the derived point‐of‐departure (PoD) values when estimating permitted daily exposure (PDE) values. A total of 40 data sets were identified from the liter...
Autores principales: | Gollapudi, Bala Bhaskar, Su, Steave, Li, Abby A., Johnson, George E., Reiss, Richard, Albertini, Richard J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756744/ https://www.ncbi.nlm.nih.gov/pubmed/32926486 http://dx.doi.org/10.1002/em.22408 |
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