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Features of increased malignancy in eosinophilic clear cell renal cell carcinoma

Clear cell renal cell carcinoma (ccRCC) is the most common form of renal cancer. Due to inactivation of the von Hippel–Lindau tumour suppressor, the hypoxia‐inducible transcription factors (HIFs) are constitutively activated in these tumours, resulting in a pseudo‐hypoxic phenotype. The HIFs induce...

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Detalles Bibliográficos
Autores principales: Nilsson, Helén, Lindgren, David, Axelson, Håkan, Brueffer, Christian, Saal, Lao H, Lundgren, Jaana, Johansson, Martin E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756750/
https://www.ncbi.nlm.nih.gov/pubmed/32815150
http://dx.doi.org/10.1002/path.5532