Asymmetric Biocatalytic Synthesis of 1‐Aryltetrahydro‐β‐carbolines Enabled by “Substrate Walking”

Stereoselective catalysts for the Pictet–Spengler reaction of tryptamines and aldehydes may allow a simple and fast approach to chiral 1‐substituted tetrahydro‐β‐carbolines. Although biocatalysts have previously been employed for the Pictet–Spengler reaction, not a single one accepts benzaldehyde an...

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Detalles Bibliográficos
Autores principales: Eger, Elisabeth, Schrittwieser, Joerg H., Wetzl, Dennis, Iding, Hans, Kuhn, Bernd, Kroutil, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756766/
https://www.ncbi.nlm.nih.gov/pubmed/33017078
http://dx.doi.org/10.1002/chem.202004449

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756766/
https://www.ncbi.nlm.nih.gov/pubmed/33017078
http://dx.doi.org/10.1002/chem.202004449

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