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Microglial phagocytosis dysfunction in the dentate gyrus is related to local neuronal activity in a genetic model of epilepsy

OBJECTIVE: Microglial phagocytosis of apoptotic cells is an essential component of the brain regenerative response during neurodegeneration. Whereas it is very efficient in physiological conditions, it is impaired in mouse and human mesial temporal lobe epilepsy, and now we extend our studies to a m...

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Detalles Bibliográficos
Autores principales: Sierra‐Torre, Virginia, Plaza‐Zabala, Ainhoa, Bonifazi, Paolo, Abiega, Oihane, Díaz‐Aparicio, Irune, Tegelberg, Saara, Lehesjoki, Anna‐Elina, Valero, Jorge, Sierra, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756777/
https://www.ncbi.nlm.nih.gov/pubmed/32940364
http://dx.doi.org/10.1111/epi.16692