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Unravelling the Time Scale of Conformational Plasticity and Allostery in Glycan Recognition by Human Galectin‐1

The interaction of human galectin‐1 with a variety of oligosaccharides, from di‐(N‐acetyllactosamine) to tetra‐saccharides (blood B type‐II antigen) has been scrutinized by using a combined approach of different NMR experiments, molecular dynamics (MD) simulations, and isothermal titration calorimet...

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Detalles Bibliográficos
Autores principales: Bertuzzi, Sara, Gimeno, Ana, Núñez‐Franco, Reyes, Bernardo‐Seisdedos, Ganeko, Delgado, Sandra, Jiménez‐Osés, Gonzalo, Millet, Oscar, Jiménez‐Barbero, Jesús, Ardá, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756784/
https://www.ncbi.nlm.nih.gov/pubmed/32780906
http://dx.doi.org/10.1002/chem.202003212