Proteostasis in dendritic cells is controlled by the PERK signaling axis independently of ATF4

In stressed cells, phosphorylation of eukaryotic initiation factor 2α (eIF2α) controls transcriptome-wide changes in mRNA translation and gene expression known as the integrated stress response. We show here that DCs are characterized by high eIF2α phosphorylation, mostly caused by the activation of...

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Detalles Bibliográficos
Autores principales: Mendes, Andreia, Gigan, Julien P, Rodriguez Rodrigues, Christian, Choteau, Sébastien A, Sanseau, Doriane, Barros, Daniela, Almeida, Catarina, Camosseto, Voahirana, Chasson, Lionel, Paton, Adrienne W, Paton, James C, Argüello, Rafael J, Lennon-Duménil, Ana-Maria, Gatti, Evelina, Pierre, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756897/
https://www.ncbi.nlm.nih.gov/pubmed/33443099
http://dx.doi.org/10.26508/lsa.202000865

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756897/
https://www.ncbi.nlm.nih.gov/pubmed/33443099
http://dx.doi.org/10.26508/lsa.202000865

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