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Proteostasis in dendritic cells is controlled by the PERK signaling axis independently of ATF4
In stressed cells, phosphorylation of eukaryotic initiation factor 2α (eIF2α) controls transcriptome-wide changes in mRNA translation and gene expression known as the integrated stress response. We show here that DCs are characterized by high eIF2α phosphorylation, mostly caused by the activation of...
Autores principales: | Mendes, Andreia, Gigan, Julien P, Rodriguez Rodrigues, Christian, Choteau, Sébastien A, Sanseau, Doriane, Barros, Daniela, Almeida, Catarina, Camosseto, Voahirana, Chasson, Lionel, Paton, Adrienne W, Paton, James C, Argüello, Rafael J, Lennon-Duménil, Ana-Maria, Gatti, Evelina, Pierre, Philippe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756897/ https://www.ncbi.nlm.nih.gov/pubmed/33443099 http://dx.doi.org/10.26508/lsa.202000865 |
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