CRISPR-Cas9 Ribonucleoprotein-Mediated Genomic Editing in Primary Innate Immune Cells

CRISPR-Cas9 genome engineering can be used to functionally investigate the complex mechanisms of immune system regulation. Decades of work have aimed to genetically reprogram innate immunity, but current approaches are inefficient or nonspecific, limiting their use. Here, we detail an optimized stra...

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Detalles Bibliográficos
Autores principales: Hildreth, Andrew D., Riggan, Luke, O’Sullivan, Timothy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756923/
https://www.ncbi.nlm.nih.gov/pubmed/33377009
http://dx.doi.org/10.1016/j.xpro.2020.100113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756923/
https://www.ncbi.nlm.nih.gov/pubmed/33377009
http://dx.doi.org/10.1016/j.xpro.2020.100113

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