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Characterisation of plasmodial transketolases and identification of potential inhibitors: an in silico study

BACKGROUND: Plasmodial transketolase (PTKT) enzyme is one of the novel pharmacological targets being explored as potential anti-malarial drug target due to its functional role and low sequence identity to the human enzyme. Despite this, features contributing to such have not been exploited for anti-...

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Detalles Bibliográficos
Autores principales: Boateng, Rita Afriyie, Tastan Bishop, Özlem, Musyoka, Thommas Mutemi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756947/
https://www.ncbi.nlm.nih.gov/pubmed/33256744
http://dx.doi.org/10.1186/s12936-020-03512-1