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Characterisation of plasmodial transketolases and identification of potential inhibitors: an in silico study
BACKGROUND: Plasmodial transketolase (PTKT) enzyme is one of the novel pharmacological targets being explored as potential anti-malarial drug target due to its functional role and low sequence identity to the human enzyme. Despite this, features contributing to such have not been exploited for anti-...
Autores principales: | Boateng, Rita Afriyie, Tastan Bishop, Özlem, Musyoka, Thommas Mutemi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756947/ https://www.ncbi.nlm.nih.gov/pubmed/33256744 http://dx.doi.org/10.1186/s12936-020-03512-1 |
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