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Full-length and C-terminal neurogranin in Alzheimer’s disease cerebrospinal fluid analyzed by novel ultrasensitive immunoassays

BACKGROUND: Neurogranin (Ng) is a neuron-specific and postsynaptic protein that is abundantly expressed in the brain, particularly in the dendritic spine of the hippocampus and cerebral cortex. The enzymatic cleavage of Ng produces fragments that are released into cerebrospinal (CSF), which have bee...

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Detalles Bibliográficos
Autores principales: Öhrfelt, Annika, Dumurgier, Julien, Zetterberg, Henrik, Vrillon, Agathe, Ashton, Nicholas J., Kvartsberg, Hlin, Bouaziz-Amar, Elodie, Hugon, Jacques, Paquet, Claire, Blennow, Kaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756958/
https://www.ncbi.nlm.nih.gov/pubmed/33353563
http://dx.doi.org/10.1186/s13195-020-00748-6