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Superparamagnetic Nanoparticles for Lysosome Isolation to Identify Spatial Alterations in Lysosomal Protein and Lipid Composition

Lysosomes are dynamic organelles that serve as regulatory hubs in cellular homeostasis. Changes in lysosome morphology, composition, and turnover are typically linked to disease. These characteristics make enrichment protocols based on biophysical parameters challenging. However, organelle enrichmen...

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Detalles Bibliográficos
Autores principales: Tharkeshwar, Arun Kumar, Demedts, David, Annaert, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756972/
https://www.ncbi.nlm.nih.gov/pubmed/33377016
http://dx.doi.org/10.1016/j.xpro.2020.100122