Assessing the Safety of a Cell-Based Immunotherapy for Brain Cancers Using a Humanized Model of Hematopoiesis

Despite a surge in the preclinical development of immunotherapies, current models are unable to predict putative toxicity, particularly the “on-target, off-tumor” effects of these therapeutics. To address this gap, we used a humanized mouse model of hematopoiesis to examine the toxicity profile of C...

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Detalles Bibliográficos
Autores principales: Salim, Sabra K., Xu, Joshua, Wong, Nicholas, Venugopal, Chitra, Hope, Kristin J., Singh, Sheila K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756979/
https://www.ncbi.nlm.nih.gov/pubmed/33377018
http://dx.doi.org/10.1016/j.xpro.2020.100124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7756979/
https://www.ncbi.nlm.nih.gov/pubmed/33377018
http://dx.doi.org/10.1016/j.xpro.2020.100124

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