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Enhancement of cisplatin sensitivity in human breast cancer MCF-7 cell line through BiP and 14-3-3ζ co-knockdown

Cisplatin treatment confers the relative resistance to MCF-7 cells as compared to other breast cancer cell lines. One principal reason is that chemotherapeutic agents induce autophagy in these cells to inhibit apoptosis. Binding immunoglobulin protein (BiP), a master regulator of unfolded protein re...

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Detalles Bibliográficos
Autores principales: Kashkoulinejad-Kouhi, Tahereh, Safarian, Shahrokh, Arnaiz, Blanca, Saa, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757084/
https://www.ncbi.nlm.nih.gov/pubmed/33416155
http://dx.doi.org/10.3892/or.2020.7898