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Novel quinazolinone MJ-33 induces AKT/mTOR-mediated autophagy-associated apoptosis in 5FU-resistant colorectal cancer cells

Novel quinazolinone compounds have been studied in the field of drug discovery for a long time. Among their broad range of pharmacological effects, certain compounds effectively inhibit cancer cell proliferation. MJ-33 is a quinazolinone derivative with proposed anticancer activities that was synthe...

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Detalles Bibliográficos
Autores principales: Ha, Hai-Anh, Chiang, Jo-Hua, Tsai, Fuu-Jen, Bau, Da-Tian, Juan, Yu-Ning, Lo, Yu-Hsiang, Hour, Mann-Jen, Yang, Jai-Sing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757098/
https://www.ncbi.nlm.nih.gov/pubmed/33416156
http://dx.doi.org/10.3892/or.2020.7882