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Protocol for Probing Regulated Lysosomal Activity and Function in Living Cells

Lysosomes are the catabolic center of the cell. Limitations of many lysosomal tracers include low specificity and lack of reliable physiological readouts for changes in growth factor-regulated lysosomal activity. The imaging-based protocols described here provide insights at the cellular level to qu...

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Detalles Bibliográficos
Autores principales: Albrecht, L.V., Tejeda-Muñoz, N., De Robertis, E.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757114/
https://www.ncbi.nlm.nih.gov/pubmed/33377026
http://dx.doi.org/10.1016/j.xpro.2020.100132