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Protocol for the Generation of Definitive Hematopoietic Progenitors from Human Pluripotent Stem Cells

This protocol offers a detailed procedure for the in vitro differentiation of human pluripotent stem cells (hPSCs) to multipotent hematopoietic progenitors that arise from SOX17(+) hemogenic endothelium, mimicking intra-embryonic, HOXA-positive, aorta-gonad mesonephros (AGM) hematopoiesis. The gener...

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Detalles Bibliográficos
Autores principales: Nafria, Monica, Bonifer, Constanze, Stanley, Edouard Guy, Ng, Elizabeth Siewsun, Elefanty, Andrew George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757115/
https://www.ncbi.nlm.nih.gov/pubmed/33377024
http://dx.doi.org/10.1016/j.xpro.2020.100130