Inactivation of HIF‐prolyl 4‐hydroxylases 1, 2 and 3 in NG2‐expressing cells induces HIF2‐mediated neurovascular expansion independent of erythropoietin

AIM: NG2 cells in the brain are comprised of pericytes and NG2 glia and play an important role in the execution of cerebral hypoxia responses, including the induction of erythropoietin (EPO) in pericytes. Oxygen‐dependent angiogenic responses are regulated by hypoxia‐inducible factor (HIF), the acti...

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Detalles Bibliográficos
Autores principales: Urrutia, Andrés A., Guan, Nan, Mesa‐Ciller, Claudia, Afzal, Aqeela, Davidoff, Olena, Haase, Volker H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Cardiovascular Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757172/
https://www.ncbi.nlm.nih.gov/pubmed/32846048
http://dx.doi.org/10.1111/apha.13547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757172/
https://www.ncbi.nlm.nih.gov/pubmed/32846048
http://dx.doi.org/10.1111/apha.13547

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