Highly sensitive HPLC analysis and biophysical characterization of N‐glycans of IgG‐Fc domain in comparison between CHO and 293 cells using FcγRIIIa ligand

Quality control of monoclonal antibodies is challenging due in part to the diversity of post‐translational modifications present. The regulation of the N‐glycans of IgG‐Fc domain is one of the key factors to maintain the safety and efficacy of antibody drugs. The FcγRIIIa affinity column is an attra...

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Detalles Bibliográficos
Autores principales: Kosuge, Hirofumi, Nagatoishi, Satoru, Kiyoshi, Masato, Ishii‐Watabe, Akiko, Tanaka, Toru, Terao, Yosuke, Oe, Seigo, Ide, Teruhiko, Tsumoto, Kouhei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
RESEARCH ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757244/
https://www.ncbi.nlm.nih.gov/pubmed/32390308
http://dx.doi.org/10.1002/btpr.3016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757244/
https://www.ncbi.nlm.nih.gov/pubmed/32390308
http://dx.doi.org/10.1002/btpr.3016

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