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Dysregulation of the histone demethylase KDM6B in alcohol dependence is associated with epigenetic regulation of inflammatory signaling pathways

Epigenetic enzymes oversee long‐term changes in gene expression by integrating genetic and environmental cues. While there are hundreds of enzymes that control histone and DNA modifications, their potential roles in substance abuse and alcohol dependence remain underexplored. A few recent studies ha...

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Detalles Bibliográficos
Autores principales: Johnstone, Andrea L., Andrade, Nadja S., Barbier, Estelle, Khomtchouk, Bohdan B., Rienas, Christopher A., Lowe, Kenneth, Van Booven, Derek J., Domi, Esi, Esanov, Rustam, Vilca, Samara, Tapocik, Jenica D., Rodriguez, Keli, Maryanski, Danielle, Keogh, Michael Christopher, Meinhardt, Marcus W., Sommer, Wolfgang H., Heilig, Markus, Zeier, Zane, Wahlestedt, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757263/
https://www.ncbi.nlm.nih.gov/pubmed/31373129
http://dx.doi.org/10.1111/adb.12816