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Using Machine Learning and Targeted Mass Spectrometry to Explore the Methyl-Lys Proteome
Protein lysine methylation mediates a variety of biological processes, and their dysregulation has been established to play pivotal roles in human disease. A number of these sites constitute attractive drug targets. However, systematic identification of methylation sites is challenging and resource...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757287/ https://www.ncbi.nlm.nih.gov/pubmed/33377029 http://dx.doi.org/10.1016/j.xpro.2020.100135 |