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An Improved Protocol for Establishment of AML Patient-Derived Xenograft Models
Patient-derived xenografts (PDXs) are the most valuable tool for preclinical drug testing because they retain the genetic diversity and phenotypic heterogeneity of the original tumor. Acute myeloid leukemia (AML) remains difficult to engraft in immunodeficient mice. This is particularly true for lon...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757302/ https://www.ncbi.nlm.nih.gov/pubmed/33377050 http://dx.doi.org/10.1016/j.xpro.2020.100156 |