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An Improved Protocol for Establishment of AML Patient-Derived Xenograft Models

Patient-derived xenografts (PDXs) are the most valuable tool for preclinical drug testing because they retain the genetic diversity and phenotypic heterogeneity of the original tumor. Acute myeloid leukemia (AML) remains difficult to engraft in immunodeficient mice. This is particularly true for lon...

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Detalles Bibliográficos
Autores principales: Hassan, Nunki, Yang, Jonason, Wang, Jenny Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757302/
https://www.ncbi.nlm.nih.gov/pubmed/33377050
http://dx.doi.org/10.1016/j.xpro.2020.100156