Cargando…

Sensitization of Non-permissive Laboratory Mice to SARS-CoV-2 with a Replication-Deficient Adenovirus Expressing Human ACE2

Common laboratory mice such as BALB/c and C57BL/6 mice are not permissive to SARS-CoV2 infection. Sensitization of laboratory mice with Adenovirus expressing human ACE2 (Ad5-hACE2) provides a rapid model for testing viral intervention in vivo. Despite the lack of lethal outcome, Ad5-hACE2-sensitized...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wong, Lok-Yin Roy, Li, Kun, Sun, Jing, Zhuang, Zhen, Zhao, Jincun, McCray, Paul B., Perlman, Stanley
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2020
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757354/ https://www.ncbi.nlm.nih.gov/pubmed/33377063 http://dx.doi.org/10.1016/j.xpro.2020.100169

Ejemplares similares

COVID-19 Treatments and Pathogenesis Including Anosmia in K18-hACE2 mice
por: Zheng, Jian, et al.
Publicado: (2020)

Infection of Human Airway Epithelia by Sars Coronavirus is Associated with ACE2 Expression and Localization
por: Jia, Hong Peng, et al.
Publicado: (2006)

Mice Humanized for MHC and hACE2 with High Permissiveness to SARS-CoV-2 Omicron Replication
por: Le Chevalier, Fabien, et al.
Publicado: (2023)

Valganciclovir Inhibits Human Adenovirus Replication and Pathology in Permissive Immunosuppressed Female and Male Syrian Hamsters
por: Toth, Karoly, et al.
Publicado: (2015)

Chinese tree shrew: a permissive model for in vitro and in vivo replication of human adenovirus species B
por: Li, Xiao, et al.
Publicado: (2021)

Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses — are we our own worst enemy?
por: Wong, Lok-Yin Roy, et al.
Publicado: (2021)

Author Correction: Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses — are we our own worst enemy?
por: Wong, Lok-Yin Roy, et al.
Publicado: (2021)

Middle East Respiratory Syndrome Coronavirus Causes Multiple Organ Damage and Lethal Disease in Mice Transgenic for Human Dipeptidyl Peptidase 4
por: Li, Kun, et al.
Publicado: (2016)

The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases
por: Earnest, James T., et al.
Publicado: (2017)

Differential Effects of IL-12 on Tregs and Non-Treg T Cells: Roles of IFN-γ, IL-2 and IL-2R
por: Zhao, Jingxian, et al.
Publicado: (2012)

Human adenovirus type 5 vectors deleted of early region 1 (E1) undergo limited expression of early replicative E2 proteins and DNA replication in non-permissive cells
por: Saha, Bratati, et al.
Publicado: (2017)

Heat shock protein 72 expression allows permissive replication of oncolytic adenovirus dl1520 (ONYX-015) in rat glioblastoma cells
por: Madara, Jonathan, et al.
Publicado: (2005)

Immunization of MERS-CoV-2-infected mice with a sublethal dose of MERS-CoV or VRP-MERS-S
por: Zheng, Jian, et al.
Publicado: (2023)

Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract
por: Ortiz, Miguel E., et al.
Publicado: (2020)

Paradoxical modulation of influenza by intranasal administration of non-replicating adenovirus particles
por: Tang, De-chu Christopher
Publicado: (2020)

Human mesenchymal stromal cells do not express ACE2 and TMPRSS2 and are not permissive to SARS‐CoV‐2 infection
por: Avanzini, Maria A., et al.
Publicado: (2021)

Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract
por: Ortiz Bezara, Miguel E., et al.
Publicado: (2020)

Proviral role of caspase-6 in coronavirus infections
por: Wong, Lok-Yin Roy, et al.
Publicado: (2022)

Prospects of Replication-Deficient Adenovirus Based Vaccine Development against SARS-CoV-2
por: Garofalo, Mariangela, et al.
Publicado: (2020)

Defects in Innate Immunity Render Breast Cancer Initiating Cells Permissive to Oncolytic Adenovirus
por: Ahtiainen, Laura, et al.
Publicado: (2010)

Human Coronavirus EMC Is Not the Same as Severe Acute Respiratory Syndrome Coronavirus
por: Perlman, Stanley, et al.
Publicado: (2013)

Immune responses to SARS-CoV-2 infection in Humans and ACE2 humanized mice
por: Zhu, Airu, et al.
Publicado: (2021)

Replication of two porcine parvovirus isolates at non-permissive temperatures
por: Choi, C. S., et al.
Publicado: (1990)

Detection of SARS-CoV-2 spike protein binding to ACE2 in living cells by TR-FRET
por: Cecon, Erika, et al.
Publicado: (2021)

Protocol for infecting and monitoring susceptible k18-hACE2 mice with SARS-CoV-2
por: Couto, Joana, et al.
Publicado: (2023)

Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection
por: Li, Kun, et al.
Publicado: (2020)

The TMPRSS2 Inhibitor Nafamostat Reduces SARS-CoV-2 Pulmonary Infection in Mouse Models of COVID-19
por: Li, Kun, et al.
Publicado: (2021)

Synthetic riboswitches for external regulation of genes transferred by replication-deficient and oncolytic adenoviruses
por: Ketzer, Patrick, et al.
Publicado: (2012)

Construction and Characterization of a Novel Recombinant Attenuated and Replication-Deficient Candidate Human Adenovirus Type 3 Vaccine: “Adenovirus Vaccine Within an Adenovirus Vector”
por: Yan, Yuqian, et al.
Publicado: (2020)

Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication
por: Aagaard, Kjersti M., et al.
Publicado: (2017)

Mast cells are permissive for rhinovirus replication: potential implications for asthma exacerbations
por: Akoto, C., et al.
Publicado: (2017)

Replication Fork Reactivation in a dnaC2 Mutant at Non-Permissive Temperature in Escherichia coli
por: Saifi, Boubekeur, et al.
Publicado: (2012)

Comparison of Transgenic and Adenovirus hACE2 Mouse Models for SARS-CoV-2 Infection
por: Rathnasinghe, Raveen, et al.
Publicado: (2020)

Comparison of transgenic and adenovirus hACE2 mouse models for SARS-CoV-2 infection
por: Rathnasinghe, Raveen, et al.
Publicado: (2020)

ACE2 chromogenic immunostaining protocol optimized for formalin-fixed paraffin-embedded human tissue sections
por: Jorgensen, Marda, et al.
Publicado: (2021)

Autocrine Interferon Priming in Macrophages but Not Dendritic Cells Results in Enhanced Cytokine and Chemokine Production after Coronavirus Infection
por: Zhou, Haixia, et al.
Publicado: (2010)

T cell-mediated immune response to respiratory coronaviruses
por: Channappanavar, Rudragouda, et al.
Publicado: (2014)

Virus-Specific Regulatory T Cells Ameliorate Encephalitis by Repressing Effector T Cell Functions from Priming to Effector Stages
por: Zhao, Jingxian, et al.
Publicado: (2014)

Development of a Mouse-Adapted MERS Coronavirus
por: Li, Kun, et al.
Publicado: (2019)

The first few days of a SARS-CoV-2 infection viewed at single-cell resolution
por: Gallagher, Tom, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_hlsb4miaq99880fjoa8oo4oajv