Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model

Polycystic ovary syndrome (PCOS), a metabolic and reproductive disease, is frequently associated with type 2 diabetes. We have demonstrated activating autoantibodies (AAb) directed toward the second extracellular loop (ECL2) of the gonadotropin‐releasing hormone receptor (GnRHR) are present in a sig...

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Detalles Bibliográficos
Autores principales: Li, Hongliang, Zhang, Gege, Guo, Yankai, Deng, Jielin, Fischer, Hayley, Craig, LaTasha B., Kem, David C., Yu, Xichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757370/
https://www.ncbi.nlm.nih.gov/pubmed/33356018
http://dx.doi.org/10.14814/phy2.14672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757370/
https://www.ncbi.nlm.nih.gov/pubmed/33356018
http://dx.doi.org/10.14814/phy2.14672

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