Generation of Casp8(FL122/123GG) Mice Using CRISPR-Cas9 Technology

The purpose of this protocol is to describe the generation of missense mutations in mice using CRISPR-Cas9 technology. The current protocol focuses on the generation of a Casp8(FL122/123GG) missense mutation, but it can be adapted to introduce any missense or nonsense mutation. For complete details...

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Detalles Bibliográficos
Autores principales: Pelletier, Stephane, Tummers, Bart, Green, Douglas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757410/
https://www.ncbi.nlm.nih.gov/pubmed/33377075
http://dx.doi.org/10.1016/j.xpro.2020.100181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757410/
https://www.ncbi.nlm.nih.gov/pubmed/33377075
http://dx.doi.org/10.1016/j.xpro.2020.100181

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