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Establishing Human Male and Female Models of Cholinergic Neurons via Neurokine-Mediated Differentiation of LA-N-2 and LA-N-5 Neuroblastoma Cells

Cholinergic neurons control numerous primate-specific and sexually dimorphic brain functions. Here, we present our differentiation protocol for the closely related human female and male neuroblastoma-originated cell lines LA-N-2 and LA-N-5. Pro-cholinergic differentiation (with upregulation of choli...

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Detalles Bibliográficos
Autores principales: Lobentanzer, Sebastian, Klein, Jochen, Soreq, Hermona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757554/
https://www.ncbi.nlm.nih.gov/pubmed/33377087
http://dx.doi.org/10.1016/j.xpro.2020.100193