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A Cell-Based Assay Optimized for High-Content Cilia Imaging with Primary Rat Hippocampal Neurons

Genetic manipulations of dissociated rodent neurons provide translatable in vitro models for disease-driven phenotypes. Cilia are cellular antenna with a role in neuronal maturation and function often perturbed in neurodevelopmental disorders. Efforts for automated imaging of these microscopic protr...

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Detalles Bibliográficos
Autores principales: Di Nardo, Alessia, Vasquez, Sara, Sahin, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757556/
https://www.ncbi.nlm.nih.gov/pubmed/33377083
http://dx.doi.org/10.1016/j.xpro.2020.100189