Protocol for brain-wide or region-specific microglia depletion and repopulation in adult mice

The advent of tools enabling the direct manipulation of microglia has furthered our understanding of their role in health and disease. Here, we present a detailed protocol allowing for microglia turnover in adult CX(3)CR(1)(creERT2) × iDTR or CX(3)CR(1)(creERT2) × iDTR × tdTomato(flox) mice, either...

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Detalles Bibliográficos
Autores principales: Willis, Emily F., Vukovic, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757678/
https://www.ncbi.nlm.nih.gov/pubmed/33377105
http://dx.doi.org/10.1016/j.xpro.2020.100211

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757678/
https://www.ncbi.nlm.nih.gov/pubmed/33377105
http://dx.doi.org/10.1016/j.xpro.2020.100211

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