Novel Type V-A CRISPR Effectors Are Active Nucleases with Expanded Targeting Capabilities

Cas12a enzymes are quickly being adopted for use in a variety of genome-editing applications. These programmable nucleases are part of adaptive microbial immune systems, the natural diversity of which has been largely unexplored. Here, we identified novel families of Type V-A CRISPR nucleases throug...

Descripción completa

Detalles Bibliográficos
Autores principales: Aliaga Goltsman, Daniela S., Alexander, Lisa M., Devoto, Audra E., Albers, Justine B., Liu, Jason, Butterfield, Cristina N., Brown, Christopher T., Thomas, Brian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2020
Materias:
Research Articles: Expanding the CRISPR Toolbox
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757703/
https://www.ncbi.nlm.nih.gov/pubmed/33146573
http://dx.doi.org/10.1089/crispr.2020.0043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757703/
https://www.ncbi.nlm.nih.gov/pubmed/33146573
http://dx.doi.org/10.1089/crispr.2020.0043

Ejemplares similares