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Novel Type V-A CRISPR Effectors Are Active Nucleases with Expanded Targeting Capabilities
Cas12a enzymes are quickly being adopted for use in a variety of genome-editing applications. These programmable nucleases are part of adaptive microbial immune systems, the natural diversity of which has been largely unexplored. Here, we identified novel families of Type V-A CRISPR nucleases throug...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Mary Ann Liebert, Inc., publishers
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757703/ https://www.ncbi.nlm.nih.gov/pubmed/33146573 http://dx.doi.org/10.1089/crispr.2020.0043 |