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Therapeutic blockade of CXCR2 rapidly clears inflammation in arthritis and atopic dermatitis models: demonstration with surrogate and humanized antibodies

Neutrophils are the most abundant effector cells of the innate immune system and represent the first line of defense against infection. However, in many common pathologies, including autoimmune diseases, excessive recruitment and activation of neutrophils can drive a chronic inflammatory response le...

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Detalles Bibliográficos
Autores principales: Alam, Md Jahangir, Xie, Liang, Ang, Caroline, Fahimi, Farnaz, Willingham, Stephen B., Kueh, Andrew J., Herold, Marco J., Mackay, Charles R., Robert, Remy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757791/
https://www.ncbi.nlm.nih.gov/pubmed/33347356
http://dx.doi.org/10.1080/19420862.2020.1856460