Cargando…

Biparental contributions of the H2A.B histone variant control embryonic development in mice

Histone variants expand chromatin functions in eukaryote genomes. H2A.B genes are testis-expressed short histone H2A variants that arose in placental mammals. Their biological functions remain largely unknown. To investigate their function, we generated a knockout (KO) model that disrupts all 3 H2A....

Descripción completa

Detalles Bibliográficos
Autores principales: Molaro, Antoine, Wood, Anna J., Janssens, Derek, Kindelay, Selina M., Eickbush, Michael T., Wu, Steven, Singh, Priti, Muller, Charles H., Henikoff, Steven, Malik, Harmit S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757805/
https://www.ncbi.nlm.nih.gov/pubmed/33362208
http://dx.doi.org/10.1371/journal.pbio.3001001