Cargando…

Novel CRISPR-based sequence specific enrichment methods for target loci and single base mutations

The programmable sequence specificity of CRISPR has found uses in gene editing and diagnostics. This manuscript describes an additional application of CRISPR through a family of novel DNA enrichment technologies. CAMP (CRISPR Associated Multiplexed PCR) and cCAMP (chimeric CRISPR Associated Multiple...

Descripción completa

Detalles Bibliográficos
Autores principales: Steele, Jennifer L., Stevens, Richard C., Cabrera, Oscar A., Bassill, Gary J., Cramer, Sabrina M., Guzman, Felipe, Shuber, Anthony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757808/
https://www.ncbi.nlm.nih.gov/pubmed/33362267
http://dx.doi.org/10.1371/journal.pone.0243781