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Gene and protein expression of mTOR and LC3 in hepatocellular carcinoma, colorectal liver metastasis and “normal” liver tissues

The physiological role of autophagy in the progression of liver diseases is still debated. To understand the clinical relevance of autophagy in primary e secondary hepatic tumors, we analyzed the expression of mTOR (mammalian target of rapamycin), a key regulator of autophagy; Raptor (regulatory-ass...

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Detalles Bibliográficos
Autores principales: Bortolami, Marina, Comparato, Alessandra, Benna, Clara, Errico, Andrea, Maretto, Isacco, Pucciarelli, Salvatore, Cillo, Umberto, Farinati, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757890/
https://www.ncbi.nlm.nih.gov/pubmed/33362215
http://dx.doi.org/10.1371/journal.pone.0244356