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A Randomized, Open, Single-Centre, Crossed Study of the Effect of Food on the Pharmacokinetics of One Oral Dose of Alflutinib Mesylate Tablets (AST2818) in Healthy Male Subjects

The aim of the study was to study the PK of AST2818 tablets after one oral dose in healthy male subjects on an empty stomach and in a postprandial state and to evaluate the effect of food on AST2818 bioavailability. Sixteen healthy Chinese male subjects were randomly divided into two groups: a fasti...

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Detalles Bibliográficos
Autores principales: Zhu, Songlin, Deng, Jun, Tang, Qi, Heng, Jianfu, Qu, Jingjing, Chen, Yong, Chen, Xue, Yang, Nong, Liu, Xiaobao, Li, Kunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757978/
https://www.ncbi.nlm.nih.gov/pubmed/33680007
http://dx.doi.org/10.22037/ijpr.2020.113112.14116