Structure Prediction and Expression of Modified rCTLA4-Ig as a Blocker for B7 Molecules

CTLA4-Ig (Abatacept) has been produced to suppress immune response by inhibition of T cells functions in autoimmune disease. A new drug, which is called belatacept, has recently been recently developed that is more efficient. The development has been occurred by two substitutions (A29Y, L104E) in th...

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Detalles Bibliográficos
Autores principales: Mahdizadeh, Hossein, Salimian, Jafar, Noormohammadi, Zahra, Amani, Jafar, Halabian, Raheleh, Panahi, Yunes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757981/
https://www.ncbi.nlm.nih.gov/pubmed/33680034
http://dx.doi.org/10.22037/ijpr.2020.112959.14040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757981/
https://www.ncbi.nlm.nih.gov/pubmed/33680034
http://dx.doi.org/10.22037/ijpr.2020.112959.14040

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