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Synthesis and Bioactivity of a Cyclopolypeptide from Caribbean Marine Sponge

Synthesis of a natural proline-rich cyclopolypeptide - rolloamide A was carried out by coupling of tri- and tetrapeptide units Boc-Phe-Pro-Val-OMe and Boc-Pro-Leu-Pro-Ile-OMe after proper deprotection at carboxyl and amino terminals using carbodiimide chemistry in alkaline environment followed by cy...

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Detalles Bibliográficos
Autores principales: Dahiya, Rajiv, Rampersad, Stacy, Ramnanansingh, Terry G., Kaur, Komalpreet, Kaur, Ramninder, Mourya, Rita, Chennupati, Suresh V., Fairman, Richard, Jalsa, Nigel K., Sharma, Ajay, Fuloria, Shivkanya, Fuloria, Neeraj Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7757994/
https://www.ncbi.nlm.nih.gov/pubmed/33680019
http://dx.doi.org/10.22037/ijpr.2020.15405.13075