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Inhibition of Cyclin-dependent Kinase (CDK) Decreased Survival of NB4 Leukemic Cells: Proposing a p53-Independent Sensitivity of Leukemic Cells to Multi-CDKs Inhibitor AT7519

An unbounded number of events exist beneath the intricacy of each particular hematologic malignancy, prompting the tumor cells into an unrestrained proliferation and invasion. Aberrant expression of cyclin-dependent kinases (CDKs) is one of these events which disrupts the regulation of cell cycle an...

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Detalles Bibliográficos
Autores principales: Pourbagheri-Sigaroodi, Atieh, Safaroghli-Azar, Ava, Shanaki, Mehrnoosh, Yousefi, Amir-Mohammad, Anjam Najmedini, Ali, Bashash, Davood
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758003/
https://www.ncbi.nlm.nih.gov/pubmed/33680018
http://dx.doi.org/10.22037/ijpr.2020.113170.14148