Novel piperazine–chalcone hybrids and related pyrazoline analogues targeting VEGFR-2 kinase; design, synthesis, molecular docking studies, and anticancer evaluation

New piperazine–chalcone hybrids and related pyrazoline derivatives have been designed and synthesised as potential vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors. The National Cancer Institute (NCI) has selected six compounds to evaluate their antiproliferative activity in vitro...

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Detalles Bibliográficos
Autores principales: Ahmed, Marwa F., Santali, Eman Y., El-Haggar, Radwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758046/
https://www.ncbi.nlm.nih.gov/pubmed/33349069
http://dx.doi.org/10.1080/14756366.2020.1861606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758046/
https://www.ncbi.nlm.nih.gov/pubmed/33349069
http://dx.doi.org/10.1080/14756366.2020.1861606

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