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Novel piperazine–chalcone hybrids and related pyrazoline analogues targeting VEGFR-2 kinase; design, synthesis, molecular docking studies, and anticancer evaluation

New piperazine–chalcone hybrids and related pyrazoline derivatives have been designed and synthesised as potential vascular endothelial growth factor receptor-2 (VEGFR-2) inhibitors. The National Cancer Institute (NCI) has selected six compounds to evaluate their antiproliferative activity in vitro...

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Detalles Bibliográficos
Autores principales:	Ahmed, Marwa F., Santali, Eman Y., El-Haggar, Radwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2020
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758046/ https://www.ncbi.nlm.nih.gov/pubmed/33349069 http://dx.doi.org/10.1080/14756366.2020.1861606

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