An AMPK-dependent, non-canonical p53 pathway plays a key role in adipocyte metabolic reprogramming

It has been known adipocytes increase p53 expression and activity in obesity, however, only canonical p53 functions (i.e. senescence and apoptosis) are attributed to inflammation-associated metabolic phenotypes. Whether or not p53 is directly involved in mature adipocyte metabolic regulation remains...

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Detalles Bibliográficos
Autores principales: Wang, Hong, Wan, Xueping, Pilch, Paul F, Ellisen, Leif W, Fried, Susan K, Liu, Libin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758072/
https://www.ncbi.nlm.nih.gov/pubmed/33320092
http://dx.doi.org/10.7554/eLife.63665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758072/
https://www.ncbi.nlm.nih.gov/pubmed/33320092
http://dx.doi.org/10.7554/eLife.63665

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