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An AMPK-dependent, non-canonical p53 pathway plays a key role in adipocyte metabolic reprogramming
It has been known adipocytes increase p53 expression and activity in obesity, however, only canonical p53 functions (i.e. senescence and apoptosis) are attributed to inflammation-associated metabolic phenotypes. Whether or not p53 is directly involved in mature adipocyte metabolic regulation remains...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758072/ https://www.ncbi.nlm.nih.gov/pubmed/33320092 http://dx.doi.org/10.7554/eLife.63665 |