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The Murine CD137/CD137 Ligand Signalosome: A Signal Platform Generating Signal Complexity
CD137, a member of the TNFR family, is a costimulatory receptor, and CD137L, a member of the TNF family, is its ligand. Studies using CD137- and CD137L-deficient mice and antibodies against CD137 and CD137L have revealed the diverse and paradoxical effects of these two proteins in various cancers, a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7758191/ https://www.ncbi.nlm.nih.gov/pubmed/33362756 http://dx.doi.org/10.3389/fimmu.2020.553715 |